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All designer BZDs are listed here explained and mentioned In accordance with a chronological get of visual appearance on the web drug sector and according to the notification sent out for the EMCDDA.

Deschloroetizolam provides cross-tolerance with all benzodiazepines and thienodiazepines, indicating that immediately after its intake all thienodiazepines can have a lessened result. Overdose

Nifoxipam very likely possesses a pharmacological action comparable to flunitrazepam, by binding towards the GABAA receptor, and with very similar side-consequences and toxicity [ninety five]. Nifoxipam is amazingly physically and psychologically addictive and provides cross-tolerance with all BZDs, thus decreasing their pharmacological effects [ninety five]. There are no further data about medical, pharmacological or toxicological Attributes. Nifoxipam is not really now managed underneath the 1971 United Nations Conference on Psychotropic Substances or even the 1961 One Convention on Narcotic Medication.

Acute intoxication may cause respiratory and central anxious system despair, Regardless that isn't lethal If your BDZ is taken by yourself [6]. Having said that, BZDs are usually eaten in combination with other depressant medication/substances (

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